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I gained about 30lbs on seroquel, even with such a low dose. Even if you maintained the same diet and exercise patterns pre-drug that you did while taking Seroquel, you’d probably still gain some weight. I am 6'1" and was at 205 pounds for 7 years. 4k views Reviewed >2 years ago Thank. Control weight with or without the added effects of medication. After getting home and doing some research, one of the most common side effects I’m seeing among many people is weight gain I’ve been on seroquel since I was 13, and I’m finally thinking that many of the problems I have now are because of it. Moderate exercise 30 min/day at least 5 days a wk also helps. ) Add topiramate ( Topamax) to the mix. Log every food and drink you consume each day. This change in lifestyle is the healthiest way to combat Seroquel and weight gain. I told her about that so today she prescribed Seroquel 25mg. This is due to the fact that the drug slows your metabolism. 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Also, patients should find cheap and healthy alternatives for fast food. 25mg a night for sleep or I sometimes take 12. If I don’t take it at the same time, I get manic. So I started cardio, 1 hour SIX times a week, weights at the gym 3 times a week, and basically starving myself. The weight gain was a depressing, and impossible to manage even with a change to a healthier diet and increased activity level This is the second time I have been on this medication. This explains some research on other medications that can help sometimes http://www. Of course, it depends on the individual, though.. 5mg In the past week or so, I’ve found that if I take: 1 Hydroxyzine 25mg 1 Benadryl 1 Zyrtec 2 Advil PM 2 OTC Sleep aid, then I can get about 7 hours of sleep. Choose low-calorie foods like fresh fruits and vegetables, eat fiber-rich and slow-to-digest complex carbohydrates, and drink lots of. I take it early in the evening, and when the hungar pains kick in, eat my evening meal.