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Click here to read our Diabetes and Metformin FAQs including information on lactic acidosis. [19] It was introduced as a medication in France in 1957 and the United States in 1995. Metformin hydrochloride is the scientific or generic name for the active ingredient in tablets sold in Australia under 40 different proprietary or brand names. [4] It works by decreasing glucose production by the liver and increasing the insulin sensitivity of body tissues. [8] [20] It is on the World Health Organization's List of Essential Medicines. History Metformin was originally developed from natural compounds found in the plant Galega officinalis, known as French lilac or goat’s rue Created by Bristol-Myers Squibb Company, Metformin is approved in the US and the UK as a treatment for type 2 diabetes. Hazelwood, MO 63042 Contact Details. Metformin is approved in the US and the UK as a treatment for type 2 diabetes and contains the active ingredient metformin hydrochloride (or metformin hcl).. [4] [11] Metformin is in the biguanide class. This article traces the roots of the antihyperglycaemic biguanide metformin from the use of Galega officinalis(goat’s rue or French lilac) as a herbal treatment for the symptoms of diabetes. The metformin recall noted in this post is specific to two lots in Kansas City, Missouri, the location of Nostrum Laboratories, Inc. We found the packaging of that particular version. Is made in several countries, including the U. Some of these chemicals can be toxic, however, so human studies are lacking 1 Answer - Posted in: metformin - Answer: Mallinckrodt Inc. [19] French physician Jean Sterne began the study in humans in the 1950s. Officinaliswas found to be rich in guanidine, a substance with blood glucose-lowering activity that formed the chemical basis of metformin. [4] Metformin was discovered in 1922. Metformin was discovered in 1922. Animal studies from the 1970s and 1980s established that substances in goat's rue have blood-sugar-lowering effects. Other Names for Metformin Metformin is sold both under brand names, and also as a generic drug Metformin is a man-made chemical that's closely related to a substance found in goat’s rue. [12] French physician Jean Sterne allergic to levaquin can i take cipro began study in humans in the 1950s. Metformin is an oral antidiabetic drug for the treatment of diabetes and created by Bristol-Myers Squibb Company.